Chinese Herbs and Herbal Medicine

 Essential Components, Clinical Applications and Health Benefits


Just with Paypal

Book Details
 193 p
 File Size 
 3,278 KB
 File Type
 PDF format
 978-1-63482-086-6 (eBook)
 by Nova Science Publishers, Inc 

Radix Bupleuri (Chai Hu) is one of the most commonly used herbs in the
Chinese medicine clinical practice. In Chinese medicine, it is believed that
Radix Bupleuri is acrid, cool and bitter and enters liver and gallbladder
meridians. This book discusses the use of Chinese herbs, such as Chai Hu, and
other different herbal medicines for diseases and illnesses such as atopic
dermatitis, and for cutaneous wound healing. It discusses the essential
components, clinical applications and health benefits of herbal medicine.

Chapter I – A cutaneous wound is a break in the skin integrity as a result
of physical, thermal or chemical injuries. There are many types of wounds,
such as incisions, lacerations, contusions and burns. After hemostasis occurs at
the moment of injury, the wound healing process proceeds to subsequent yet
overlapping stages, namely inflammatory, proliferative and remodeling
phases. The inflammatory phase consists of phagocytosis and microvascular
changes induced by chemical mediators. The proliferative phase mainly
involves angiogenesis, granulation tissue formation, wound contraction and reepithelialization.
In the remodeling phase, new collagen formation occurs to
strengthen the wound. In general, the strategy for wound care management is
to prevent infection and to promote healing. Currently, herbal medicine has
increasingly become a field of interest for wound care. A number of
investigations into its therapeutic roles in wound management have been
conducted in human and animal models. The well-recognized and most
studied medicinal plants include Aloe vera, Centella asiatica and Curcuma
longa. These herbs have been used for centuries in traditional Chinese
medicine and Ayurveda. Based on the existing scientific evidence, the abovementioned
herbal medicines can accelerate cutaneous wound healing and
repair by suppressing inflammation, promoting angiogenesis, inducing cellular
growth and proliferation, reducing oxidative stress in the wound, controlling
infection, and improving wound remodeling. This chapter will provide insight
into the mechanisms underlying various stages of cutaneous wound healing.

To establish a foundation of basic knowledge, the first part of the chapter
provides an overview of wound healing mechanisms, wound management
strategies, and experimental approaches to wound healing, including research
models for wounding and the evaluation of critical events during each phase of
the wound healing process. Also, a wound microcirculation study using a
dorsal skinfold chamber preparation and an intravital microscopic technique to
demonstrate cutaneous microvascular changes in vivo will be described.

Chapter II – Radix Bupleuri (Chai Hu) is one of the most commonly used
herbs in the Chinese medicine clinical practice. In Chinese medicine, it is
believed that Radix Bupleuri (Chai Hu) is acrid, cool and bitter and enters
Liver and Gallbladder meridians. It is used to reduce fever, release the
stagnation of Liver Qi and raise clear Yang. Details of its actions, indications,
contraindications, dosage and control are discussed from Chinese medicine
perspective. In Western medicine, the clinical and experimental studies have
shown that Radix Bupleuri (Chai Hu) has anti-inflammatory, antimicrobial,
antiviral, immune-regulatory and anti-tumour effects. Radix Bupleuri (Chai
Hu) also has effects on central nervous system, cardiovascular system,
digestive system and metabolism. This monograph presents details of its
pharmacodynamics, pharmacokinetics and mechanism, toxicology and
interactions as well as side effects with evidence from comprehensive
literature search. Guidelines for its use and regulatory control in different
countries are also reviewed.

Chapter III – Atopic dermatitis (AD) is a common chronic inflammatory
skin disease in children that could adversely affect their quality of life, and its
prevalence is increasing in the last few decades. As definitive cure is lacking,
there has been a considerable interest on using traditional Chinese Herbal
Medicines (CHM) as an alternative treatment for AD. However, no data are
available to provide an overview of the use of CHM for AD. In this chapter,
we explored all the available relevant literatures on the clinical applications of
CHM for AD, including its indications, contraindications, individual
medicines, formulae, regimes, effectiveness, efficacy, safety, adverse effects
and toxicity. The main objective is to review the available clinical studies on
CHM for its therapeutic use in AD patients and the potential adverse
outcomes. Over 140 literatures were identified, including the observational
designed studies (exploratory studies, descriptive studies and analytical studies
as case series, cohort studies, case-control studies, cross-sectional studies), the
experimental studies (quasi- and randomized controlled trials) and the
qualitative studies. Based on the principles and workflows from Centre for
Evidence-Based Medicine of Oxford University and Cochrane Review, only
few studies were selected for the systematic review and further meta-analysis.

The result showed that compared with modern medicine groups, combined use
of CHMs and modern medicines was significantly effective as a treatment
option for atopic dermatitis. However there was insufficient proof on its safety
although no specific safety problem was reported in the clinical trials. More
scientific evidences through comprehensive studies on the efficacy and safety
of CHM for AD are still necessary for its wider application.

The Publisher has taken reasonable care in the preparation of this book, but makes no
expressed or implied warranty of any kind and assumes no responsibility for any errors or
omissions. No liability is assumed for incidental or consequential damages in connection
with or arising out of information contained in this book. The Publisher shall not be liable
for any special, consequential, or exemplary damages resulting, in whole or in part, from
the readers’ use of, or reliance upon, this material. Any parts of this book based on
government reports are so indicated and copyright is claimed for those parts to the extent
applicable to compilations of such works.

Independent verification should be sought for any data, advice or recommendations
contained in this book. In addition, no responsibility is assumed by the publisher for any
injury and/or damage to persons or property arising from any methods, products,
instructions, ideas or otherwise contained in this publication.

This publication is designed to provide accurate and authoritative information with regard
to the subject matter covered herein. It is sold with the clear understanding that the
Publisher is not engaged in rendering legal or any other professional services. If legal or any
other expert assistance is required, the services of a competent person should be sought.

Table of Contents

Preface vii

Chapter I Herbal Medicine and Mechanisms for Cutaneous
Wound Healing 1
Juraiporn Somboonwong

Chapter II Chinese Medicinal Herb: A Clinical Monograph
of Radix Bupleuri (Chai Hu) 109
Angela Wei Hong Yang and Jenny Kreiner

Chapter III Chinese Herbal Medicines for Atopic Dermatitis:
A Systematic Review 149
Lu Li, Kam Lun Hon, Chi Chiu Wang
and Ping Chung Leung

Index 167

Published by Nova Science Publishers, Inc. † New York

Loading... Protection Status